We propose an efficient framework using the Dehornoy order for homotopy-aware multi-agent path planning in the plane. We developed a method to generate homotopically distinct solutions of multi-agent path planning problem in the plane by combining our framework with revised prioritized planning and proved its completeness under specific assumptions. Experimentally, we demonstrated that the runtime of our method grows approximately quintically with the number of agents. We also confirmed the usefulness of homotopy-awareness by showing experimentally that generation of homotopically distinct solutions by our method contributes to planning low-cost trajectories for a swarm of agents.